Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC366H596N112O104S12

DescriptionStandard

        MDFSKRLIPAALIVMLLLVATEMEPMVVEARTCESQSQRFKGACVSKTNCASVCQTEGFHGGHCRGFRRRCFCTKHC
    

Molecular Weight8614.12 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.69

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0610

GRAVY Index0.02

Hydrophobic Moment 0.59

Boman Index-0.03

Instability Index49.41

Aliphatic Index 65.84

Aromaticity 0.0649

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3479.22

LogP -37.95

H-bond Donors 132.0

H-bond Acceptors 124.0

Rotatable Bonds 289.0

Heavy Atoms 594.0

Ring Count 10.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161408 VERIFIED: NO

Provenance & Taxonomy

OrganismEucalyptus grandis [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence