Peptide Database

Peptide NameAgaDef

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC193H297N61O52S6

DescriptionStandard

        ATCDLLSKWNWNHTACAAHCIARKFKGGYCNDKAVCVCRH
    

Molecular Weight4496.19 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)4.00

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.0999

GRAVY Index-0.22

Hydrophobic Moment 0.57

Boman Index-0.04

Instability Index21.01

Aliphatic Index 58.75

Aromaticity 0.1000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1828.51

LogP -19.37

H-bond Donors 71.0

H-bond Acceptors 65.0

Rotatable Bonds 144.0

Heavy Atoms 312.0

Ring Count 9.0

Amide Bonds 42.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0369318 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila ananassae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)