Peptide Database

Peptide NameSLAY-screened peptide P3057

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H162N30O28S3

DescriptionStandard

        PSCDLWDCRFRCLTLWPTVH
    

Molecular Weight2448.84 Da

Isoelectric Point (pI)7.05

Net Charge (pH 7.0)0.02

Net Charge (pH 7.4) -0.13

Charge Density (pH 7.0) 0.0009

GRAVY Index-0.03

Hydrophobic Moment 0.38

Boman Index0.03

Instability Index78.37

Aliphatic Index 73.00

Aromaticity 0.1500

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 912.79

LogP -5.99

H-bond Donors 37.0

H-bond Acceptors 32.0

Rotatable Bonds 71.0

Heavy Atoms 171.0

Ring Count 8.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323466 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/