Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC360H585N87O118S6

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCEEEGADEDDGEEMTEEEVKRSFLSKFKDIALDVAKNAGKGVLTTLACKIDGSC
    

Molecular Weight8212.40 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-6.51

Net Charge (pH 7.4) -6.80

Charge Density (pH 7.0) -0.0867

GRAVY Index0.02

Hydrophobic Moment 0.65

Boman Index0.07

Instability Index46.58

Aliphatic Index 91.07

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3311.90

LogP -30.30

H-bond Donors 117.0

H-bond Acceptors 118.0

Rotatable Bonds 290.0

Heavy Atoms 571.0

Ring Count 5.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192679 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0414011 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial