Peptide Database

Peptide NameAtrial natriuretic factor

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC96H159N37O34S3

DescriptionStandard

        ASSCFGARMDRIGNASGLGCNNGRG
    

Molecular Weight2471.71 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0711

GRAVY Index-0.36

Hydrophobic Moment 0.52

Boman Index-0.07

Instability Index11.13

Aliphatic Index 43.20

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1174.68

LogP -20.30

H-bond Donors 44.0

H-bond Acceptors 39.0

Rotatable Bonds 83.0

Heavy Atoms 170.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034975 VERIFIED: YES

Provenance & Taxonomy

OrganismTakifugu rubripes [Animal]

FamilyAtrial natriuretic factor

Tax ID31033

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-20

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour