Peptide Database

Peptide NameMagainin 2a (M2a; Frogs, Amphibians, Animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC116H181N31O29S

DescriptionStandard

        GIGKFLHSAKKWGKAFVGEIMNS
    

Molecular Weight2505.93 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1237

GRAVY Index-0.08

Hydrophobic Moment 0.66

Boman Index0.16

Instability Index-4.61

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 972.92

LogP -7.41

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 86.0

Heavy Atoms 177.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375312 VERIFIED: YES

Provenance & Taxonomy

OrganismFrom frog [Animal]

FamilyMagainin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic

RECORD: Rec_0390044 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630