Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length376 amino acids

Chemical FormulaC1894H3012N502O519S14

DescriptionStandard

        ARLQGIAILEKELANVKLPDISGDSRIKILGKVRYEISRLDLTGFRLPLSRISLVPNVGLQVSITNAFTKVKGNWRVKLRFIRDHGSFDVTVENINININVRLGKDTAGKPTVDTSHCSTRISTVRVHFSGRLGWLYNLFHKVIESKLRKILEGKVCELQKLGEGNLHPEFLCHVALVHVFVPCFTVTTKIDAITGLDYSLVEPPTATAQSLDVAMKGEFFSMANRSAVPFAPLPLTLPLAQNRMIYFGASSYFFNTASFAYHEAGALVFEITDSMVTSPKNGDLCHCPYHLPAPLQLEEIYPDLRMKFRLFTPSAPFLSITPGGFLLKPVVDMQAYAILPNSSLVPLFLVSLVSNVSAVINVKSCHVVGTLKMGR
    

Molecular Weight41568.14 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)11.71

Net Charge (pH 7.4) 10.79

Charge Density (pH 7.0) 0.0312

GRAVY Index0.20

Hydrophobic Moment 0.65

Boman Index0.13

Instability Index37.66

Aliphatic Index 104.95

Aromaticity 0.0878

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24785.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014531 VERIFIED: NO

Provenance & Taxonomy

OrganismRostratula benghalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria