Peptide Database

Peptide NameCXCL122 (dimer)

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC353H576N106O93S6

DescriptionStandard

        KPVSLSYRCPCRFFESHVARANVKHCKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKCLNK
    

Molecular Weight7985.39 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)8.87

Net Charge (pH 7.4) 8.46

Charge Density (pH 7.0) 0.1305

GRAVY Index-0.42

Hydrophobic Moment 0.63

Boman Index-0.15

Instability Index23.80

Aliphatic Index 90.29

Aromaticity 0.0735

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3270.15

LogP -29.91

H-bond Donors 117.0

H-bond Acceptors 110.0

Rotatable Bonds 268.0

Heavy Atoms 558.0

Ring Count 12.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127625 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetCXCR4 (Human)

Activity>1000 nM

MethodKd