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MYP_108500
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Basic Information
Ranatuerin-2PLx
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C124H219N35O39S3
Standard
Sequence
GIMDTVKNAAKNLAGQLLDKLKCSITAC
Physicochemical Analysis
2920.47 Da
8.82
1.74
1.50
0.0621
0.23
0.64
0.08
6.81
108.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1217.66
-13.39
43.0
44.0
103.0
201.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112453 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0153982 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli NCTC 10418
32 μM
MIC
PaperA novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
RECORD: Rec_0207656 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Anticancer
MRSA ATCC 12493
256 μM
MIC
PaperA novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
RECORD: Rec_0232164 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
792.6 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0310340 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes: Low haemolytic activity
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
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