‹ ›
MYP_108500
← PREVIOUS NEXT → BACK
Basic Information
Ranatuerin-2PLx
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C124H219N35O39S3
Standard
Sequence
GIMDTVKNAAKNLAGQLLDKLKCSITAC
Physicochemical Analysis
2920.47 Da
8.82
1.74
1.50
0.0621
0.23
0.64
0.08
6.81
108.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1217.66
-13.39
43.0
44.0
103.0
201.0
0.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0000508 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus NCTC 10788
32 μM
MIC
PaperA novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
RECORD: Rec_0014973 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
316.9 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0072806 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Anticancer
Pseudomonas aeruginosa ATCC 27853
>512 μM
MIC
PaperA novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
RECORD: Rec_0080471 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Anticancer
Inactive: Candida albicans NCTC 1467
256 μM
MIC
PaperA novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells
RECORD: Rec_0094887 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H157
58.18 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3