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MYP_108487
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Basic Information
PACAP-related peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
48 amino acids
C227H374N68O72S2
Standard
Sequence
DVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLT
Physicochemical Analysis
5271.94 Da
5.61
-1.14
-1.41
-0.0238
-0.22
0.66
-0.05
22.67
99.79
0.0417
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2285.16
-23.10
79.0
74.0
178.0
369.0
4.0
51.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024187 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
PACAP-related peptide
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0056206 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Glucagon
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/PACA_RAT/entry
RECORD: Rec_0057421 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0082643 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
PACAP-related peptide
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0267105 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
PACAP-related peptide
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
chromaffin cells
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
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