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MYP_108473
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Basic Information
Tilapia piscidin 3, TP3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
23 amino acids
C121H182N36O26
Standard
Sequence
FIHHIIGGLFSVGKHIHSLIHGH
Physicochemical Analysis
2556.97 Da
8.79
1.28
0.77
0.0557
0.59
0.57
0.44
57.34
131.30
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.08
-5.04
33.0
33.0
82.0
183.0
8.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024064 VERIFIED: YES
Provenance & Taxonomy
Oreochromis niloticus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Baby Hamster Kidney cells BHK-21
39
CC50
PaperPubMed PMID: 30012343 PMID30012343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30012343/
RECORD: Rec_0031027 VERIFIED: NO
Provenance & Taxonomy
Oreochromis niloticus,Tilapia nilotica [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
RECORD: Rec_0039740 VERIFIED: YES
Provenance & Taxonomy
Oreochromis niloticus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Wound healing
S. agalactiae BCRC 10787
0.61 μg/mL
MIC
PaperFive Different Piscidins from Nile Tilapia, Oreochromis niloticus: Analysis of Their Expressions and Biological Functions
RECORD: Rec_0043201 VERIFIED: YES
Provenance & Taxonomy
Oreochromis niloticus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 19660
19.55 μg/mL
MIC
PMID23226256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23226256/
RECORD: Rec_0046449 VERIFIED: YES
Provenance & Taxonomy
Oreochromis niloticus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio alginolyticus
2.44 μg/mL
MIC
PMID23226256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23226256/
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