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MYP_108436
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Basic Information
Insulin-like growth factor II
Cardiovascular
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Cytokine modulation
Metabolic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
67 amino acids
C321H505N93O101S6
Standard
Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
Physicochemical Analysis
7475.40 Da
6.46
-0.24
-0.54
-0.0036
-0.22
0.91
-0.09
78.42
65.52
0.1045
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3140.78
-35.91
120.0
107.0
242.0
521.0
10.0
67.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0041460 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin-like growth factor
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-47; 21-60; 46-51
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor II (Homo sapiens): PMID 24593700 PMID24593700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24593700/
RECORD: Rec_0051056 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID12586351 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12586351/
RECORD: Rec_0061072 VERIFIED: NO
Provenance & Taxonomy
Cavia porcellus [Animal]
Insulin-like growth factor
10141
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-47; 21-60; 46-51
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation ACE inhibitory
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0176178 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
insulin family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
9-47; 21-60; 46-51
Bio-Activity Profile
Cytokine Growth factor Insulin family Growth factor signaling
PaperPDB 2V5P structural record; X-ray; 4.10 A; chain C/D; residues 1-67
RECORD: Rec_0194345 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin-like growth factor
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
9-47; 21-60; 46-51
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
glucose metabolism in adipose tissue
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Insulin-like growth factor II (Homo sapiens): PMID 24593700 PMID24593700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24593700/
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