Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length491 amino acids

Chemical FormulaC2313H3748N682O745S4

DescriptionStandard

        TPGAGGLAVSISASELSAAIAGIIAKLKKVNLKFTPFGVVLSSLIPSEIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEVAEREYENARAELEAENKNVHSLQVALDGLKNTAEGLALSDAGRHPLTSSESRFVAVPGYSGGGVHFDATATVDSRDRLNSLLSLGGAAYVNNVLELGEVSAPTEDGLKVGNAIKNAMIEVYDKLRQRLITRQNEINHAQVSLNTAIESRNKKEEKKRSAENKLNEERNKPRKGTKDYGHDYHPAPETEEIKGLGDIKKGIPKTPKQNGGGKRKRWIGDKGRKIYEWDSQHGELEGYRASDGQHLGSFDPKTGKQLKGPDPKRNIKKYL
    

Molecular Weight53158.89 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)1.35

Net Charge (pH 7.4) 0.50

Charge Density (pH 7.0) 0.0028

GRAVY Index-0.64

Hydrophobic Moment 0.73

Boman Index-0.10

Instability Index43.32

Aliphatic Index 80.00

Aromaticity 0.0428

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326842 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence