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MYP_108414
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Basic Information
Alyteserin-2Mb (toads, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
16 amino acids
C77H134N18O19
Standard
Sequence
ILGAIIPLVSGLLSHL
Physicochemical Analysis
1616.00 Da
6.74
-0.15
-0.41
-0.0095
1.96
0.36
0.72
14.31
219.38
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
560.17
-1.57
19.0
20.0
51.0
114.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321252 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0389106 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
310 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
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