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MYP_108414
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Basic Information
Alyteserin-2Mb (toads, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
16 amino acids
C77H134N18O19
Standard
Sequence
ILGAIIPLVSGLLSHL
Physicochemical Analysis
1616.00 Da
6.74
-0.15
-0.41
-0.0095
1.96
0.36
0.72
14.31
219.38
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
560.17
-1.57
19.0
20.0
51.0
114.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0262202 VERIFIED: YES
Provenance & Taxonomy
Midwife toad [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
19.3 μM
MIC
PaperAntimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): Implications for the evolution of frog skin defensive secretions.
RECORD: Rec_0278259 VERIFIED: YES
Provenance & Taxonomy
Pseudis bolbodactyla [Animal]
428381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
-
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
RECORD: Rec_0282130 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans
310 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
RECORD: Rec_0292167 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
310 μM
MIC
RECORD: Rec_0294588 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli NCTC 10418
400 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
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