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MYP_108373
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Basic Information
Insulin-like growth factor I
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
70 amino acids
C331H518N94O100S7
Standard
Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKAA
Physicochemical Analysis
7638.68 Da
7.76
0.71
0.40
0.0101
-0.24
0.46
-0.03
67.24
61.43
0.1000
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3106.70
-33.78
114.0
108.0
245.0
532.0
12.0
72.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033784 VERIFIED: NO
Provenance & Taxonomy
Suncus murinus [Animal]
Insulin
9378
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/IGF1_SUNMU/entry
RECORD: Rec_0102908 VERIFIED: NO
Provenance & Taxonomy
Suncus murinus [Animal]
Insulin-like growth factor
9378
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
bone-derived osteoblastic (PyMS) cells
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0111352 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Insulin-like growth factor
9986
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
bone-derived osteoblastic (PyMS) cells
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0148288 VERIFIED: NO
Provenance & Taxonomy
Suncus murinus [Animal]
Insulin-like growth factor
9378
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0251199 VERIFIED: NO
Provenance & Taxonomy
Suncus murinus [Animal]
Insulin-like growth factor
9378
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
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