MYP_108358
Melectin [L6V][M14,17MET-O2]
Antimicrobial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
GFLSIVKKVLPKVXAHXK
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0017186
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14,17
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
8 μM
MIC
RECORD: Rec_0128848
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14,17
Bio-Activity Profile
Antimicrobial
Bacillus subtilis 168
0.67 μM
MIC
RECORD: Rec_0129058
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14,17
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
50 μM
MIC
RECORD: Rec_0170450
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Nle= norleucine, Met (O)= methionine sulfoxide
Bio-Activity Profile
Antimicrobial
Rat erythrocytes
200 μM
LC50
RECORD: Rec_0191257
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14,17
Bio-Activity Profile
Hemolytic
human red blood cells
>200 μM
HC50
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