Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC276H438N70O86S5

DescriptionStandard

        MENEKYLQVVEDEELEQLVGGIGPGYIETLTKDCPRVTPQICVPINGIWTCKRCY
    

Molecular Weight6273.17 Da

Isoelectric Point (pI)4.48

Net Charge (pH 7.0)-4.52

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0822

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index0.04

Instability Index38.05

Aliphatic Index 90.18

Aromaticity 0.0727

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2509.97

LogP -20.52

H-bond Donors 87.0

H-bond Acceptors 87.0

Rotatable Bonds 205.0

Heavy Atoms 437.0

Ring Count 9.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360259 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

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