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MYP_108311
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C41H52N6O9
Standard
Sequence
LAYFYP
Physicochemical Analysis
772.89 Da
5.52
-0.24
-0.45
-0.0403
0.70
0.24
0.58
83.23
81.67
0.5000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
240.49
1.53
8.0
9.0
18.0
56.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133229 VERIFIED: NO
Provenance & Taxonomy
Bovine milk [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
65.0 μM
IC50
RECORD: Rec_0216988 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0287555 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
65.0
IC50
PaperPihlanto-Leppala A., Rokka T., Korhonen H.. Angiotensin I converting enzyme inhibitory peptides derived from bovine milk proteins. Int. Dairy Journal, 8, 325-331 (1998).
RECORD: Rec_0358647 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
65 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Derived from Bovine Milk Proteins | Pihlanto-Leppala, A. et al. | DOI: 10.1016/S0958-6946(98)00048-X Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
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