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MYP_108298
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Basic Information
Esculentin-1GRa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
46 amino acids
C219H366N60O58S3
Standard
Sequence
GLFSKFAGKGIKNLIFKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC
Physicochemical Analysis
4863.81 Da
9.63
4.83
4.53
0.1049
0.19
0.73
0.13
1.21
97.39
0.0652
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1904.31
-15.54
68.0
67.0
174.0
340.0
4.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0327350 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
12.5 μM
MIC
PaperJ.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami PMID16621155 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16621155/
RECORD: Rec_0331758 VERIFIED: YES
Provenance & Taxonomy
Rana grahami [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
6 μM
MIC
PMID16621155 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16621155/
RECORD: Rec_0359676 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
6.0 μM
MIC
PaperJ.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami PMID16621155 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16621155/
RECORD: Rec_0361638 VERIFIED: YES
Provenance & Taxonomy
Rana grahami [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
12.5 μM
MIC
PaperAntimicrobial peptides from diverse families isolated from the skin of the Asia frog, Rana Grahami
RECORD: Rec_0378586 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Esculentin
167935
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
6.0 μM
MIC
PaperJ.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami PMID16621155 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16621155/
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