Peptide Database

Peptide NameSLAY-screened peptide P833

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC64H93N13O23S

DescriptionStandard

        IDIPDYDYQSLC
    

Molecular Weight1444.56 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.25

Net Charge (pH 7.4) -3.47

Charge Density (pH 7.0) -0.2707

GRAVY Index-0.31

Hydrophobic Moment 0.28

Boman Index0.09

Instability Index56.83

Aliphatic Index 97.50

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 590.31

LogP -4.12

H-bond Donors 20.0

H-bond Acceptors 21.0

Rotatable Bonds 43.0

Heavy Atoms 101.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145170 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/