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MYP_108248
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Basic Information
Tyrocidine C1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C71H93N15O14
Standard
Sequence
FPWWNQYVKL
Physicochemical Analysis
1380.59 Da
8.59
0.76
0.55
0.0758
-0.48
0.40
0.22
11.27
68.00
0.4000
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
480.44
0.88
16.0
15.0
38.0
100.0
7.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026144 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Anticancer Cytotoxic
Human cervical carcinoma HeLa
16.0 μM
LC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0062158 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Listeria monocytogenes B73-MR1
16.0
MIC
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0067475 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Plasmodium falciparum 3D7
0.46 μM
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0072917 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
12.0 μM
LC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0081136 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Listeria monocytogenes B73-MR1
7.5
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
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