Peptide Database

Peptide NameSLAY-screened peptide P3815

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC59H100N20O20

DescriptionStandard

        EASLGRLHSVAAQA
    

Molecular Weight1409.55 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.30

Charge Density (pH 7.0) -0.0054

GRAVY Index0.16

Hydrophobic Moment 0.45

Boman Index0.09

Instability Index9.29

Aliphatic Index 105.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 653.05

LogP -8.50

H-bond Donors 23.0

H-bond Acceptors 21.0

Rotatable Bonds 46.0

Heavy Atoms 99.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214777 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/