Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC928H1404N208O281S7

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGLVYPAGNYTAPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVKLKLMATEIPAISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20194.75 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.52

Charge Density (pH 7.0) -0.0723

GRAVY Index0.29

Hydrophobic Moment 0.60

Boman Index0.24

Instability Index48.10

Aliphatic Index 93.88

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7727.09

LogP -81.06

H-bond Donors 262.0

H-bond Acceptors 275.0

Rotatable Bonds 638.0

Heavy Atoms 1424.0

Ring Count 37.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159047 VERIFIED: NO

Provenance & Taxonomy

OrganismChordeiles acutipennis (Lesser nighthawk) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria