Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC169H259N47O51S6

DescriptionStandard

        DHYLCVKNGGFCLYSSCPLHTKVEGTCYQGKGNCCK
    

Molecular Weight3957.54 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.87

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0520

GRAVY Index-0.34

Hydrophobic Moment 0.28

Boman Index0.01

Instability Index28.71

Aliphatic Index 48.61

Aromaticity 0.1111

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1579.95

LogP -18.30

H-bond Donors 60.0

H-bond Acceptors 61.0

Rotatable Bonds 128.0

Heavy Atoms 273.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145352 VERIFIED: YES

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)