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MYP_108179
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Basic Information
Casein beta [192-197]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C41H58N10O10
Standard
Sequence
PPHQIYP
Physicochemical Analysis
850.96 Da
7.17
0.04
-0.06
0.0064
-1.19
0.30
0.11
53.71
55.71
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
298.35
-1.03
9.0
11.0
20.0
61.0
5.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043261 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Casein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
22 μM
IC50
RECORD: Rec_0057846 VERIFIED: NO
Provenance & Taxonomy
Human milk [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
22.0 μM
IC50
RECORD: Rec_0102720 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]
9913; 9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
RECORD: Rec_0174344 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
22 μM
IC50
PaperInhibition of angiotensin I-converting enzyme by synthetic peptides of human ?-casein PMID1368548 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368548/
RECORD: Rec_0288583 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperKohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.. Inhibition of angiotensin-converting enzyme by synthetic peptides of human b-casein. Agric. Biol. Chem., 53, 2107-2114.
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