Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC926H1477N255O255S8

DescriptionStandard

        PTALPTAQEPMLLLAITEFVANSAAFTYFTAGALRRNISSNTLPRRFPLQLRTKSMGLFSPQLQEHYPDQPMELHLSARQQPLLSCHADALHGALFVSAEAFVVLPNATRVPAFLLNIDANVTGKPTINGNRLGGTVSLTGTTAPLCLPCAGLRGLPVLQVKRLETLLKFGLRLFGVPWANSECCPHPVP
    

Molecular Weight20518.71 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)5.36

Net Charge (pH 7.4) 4.96

Charge Density (pH 7.0) 0.0282

GRAVY Index0.17

Hydrophobic Moment 0.65

Boman Index0.14

Instability Index58.63

Aliphatic Index 99.16

Aromaticity 0.0684

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7986.92

LogP -97.23

H-bond Donors 275.0

H-bond Acceptors 273.0

Rotatable Bonds 646.0

Heavy Atoms 1444.0

Ring Count 38.0

Amide Bonds 206.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065224 VERIFIED: NO

Provenance & Taxonomy

OrganismSula dactylatra [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria