Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC371H609N93O118S6

DescriptionStandard

        MFPMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC
    

Molecular Weight8452.75 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-3.51

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0468

GRAVY Index-0.18

Hydrophobic Moment 0.74

Boman Index-0.03

Instability Index41.65

Aliphatic Index 87.20

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3430.07

LogP -30.57

H-bond Donors 123.0

H-bond Acceptors 121.0

Rotatable Bonds 300.0

Heavy Atoms 588.0

Ring Count 6.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244401 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0315180 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal