Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-2 precursor

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiviral

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC155H254N56O42S6

DescriptionStandard

        VTCYCRSTRCGFRERLSGACGYRGRIYRLCCR
    

Molecular Weight3766.41 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)6.67

Net Charge (pH 7.4) 6.37

Charge Density (pH 7.0) 0.2086

GRAVY Index-0.38

Hydrophobic Moment 0.67

Boman Index-0.33

Instability Index15.97

Aliphatic Index 48.75

Aromaticity 0.1250

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1639.53

LogP -19.85

H-bond Donors 71.0

H-bond Acceptors 55.0

Rotatable Bonds 123.0

Heavy Atoms 259.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410649 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide3-31; 5-20; 10-30

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus

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