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MYP_108150
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Basic Information
Neutrophil antibiotic peptide NP-2 precursor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
32 amino acids
C155H254N56O42S6
Standard
Sequence
VTCYCRSTRCGFRERLSGACGYRGRIYRLCCR
Physicochemical Analysis
3766.41 Da
9.69
6.67
6.37
0.2086
-0.38
0.67
-0.33
15.97
48.75
0.1250
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1639.53
-19.85
71.0
55.0
123.0
259.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014675 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID2254017 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
RECORD: Rec_0050078 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-31; 5-20; 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella typhimurium
PaperPubMed PMID: 2254017 | PubMed PMID: 7594610 PMID2254017;7594610 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
RECORD: Rec_0103600 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperEisenhauer P. B., Harwig S. S., Szklarek D., Ganz T., Selsted M. E., Lehrer R. I.. Purification and antimicrobial properties of three defensins from rat neutrophils. Infect. Immun., 57, 2021-2027, 1989.
RECORD: Rec_0116607 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Escherichia coli ML-35, Staphylococcus aureus 502A
PaperPurification and antimicrobial properties of three defensins from rat neutrophils
RECORD: Rec_0137989 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
PMID2254017 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
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