Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length226 amino acids

Chemical FormulaC1148H1742N258O348S9

DescriptionStandard

        IDDLTEVDYSLNSLPAVFRPFIDLDLKGIVYPTGNYTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITITEETCSYFNMSTEIFGSIIPEVAEYSPYPVMLQLMATEIPIISLEQDSLTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIAPNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25014.22 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-18.14

Net Charge (pH 7.4) -18.47

Charge Density (pH 7.0) -0.0803

GRAVY Index0.28

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index53.20

Aliphatic Index 97.12

Aromaticity 0.1283

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081597 VERIFIED: NO

Provenance & Taxonomy

OrganismEurystomus gularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria