Peptide Database

Peptide NameNeurotoxin beta-KTx 14.3

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC223H353N61O72S7

DescriptionStandard

        IAGVADLNNMSELGCPFIEKWCEDHCESKKQVGKCENFDCSCVKLGGK
    

Molecular Weight5265.01 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.56

Charge Density (pH 7.0) -0.0458

GRAVY Index-0.34

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index49.30

Aliphatic Index 62.92

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2154.27

LogP -23.02

H-bond Donors 77.0

H-bond Acceptors 78.0

Rotatable Bonds 181.0

Heavy Atoms 363.0

Ring Count 6.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224125 VERIFIED: NO

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Channel blocker

TargetKv1.1/KCNA1