Peptide Database

Peptide NameLL-37 KR-12 [K1A, R2Q]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC67H115N21O17

DescriptionStandard

        AQIVQRIKDFLR
    

Molecular Weight1486.76 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.1497

GRAVY Index-0.15

Hydrophobic Moment 0.85

Boman Index-0.20

Instability Index4.78

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 656.72

LogP -4.55

H-bond Donors 23.0

H-bond Acceptors 19.0

Rotatable Bonds 52.0

Heavy Atoms 105.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137532 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (0% Hemolysis at 100 microM

Activity100 μM

MethodHemolysis

RECORD: Rec_0207429 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli K-12

Activity240

MethodMIC