Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC363H578N104O89S8

DescriptionStandard

        MKIHLFFFILLFWVTILPARKKYPQYGSLDLRRECRKGNGRCKLECQENEIRIAYCMRPATHCCLQK
    

Molecular Weight8079.64 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.62

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.1137

GRAVY Index-0.25

Hydrophobic Moment 0.59

Boman Index-0.09

Instability Index62.06

Aliphatic Index 84.48

Aromaticity 0.1194

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3143.45

LogP -21.47

H-bond Donors 117.0

H-bond Acceptors 107.0

Rotatable Bonds 271.0

Heavy Atoms 564.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012900 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera tigris altaica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0322040 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera pardus (Leopard) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin