Peptide Database

Peptide NameOak8 cyclotide

Function Ontology

Insecticidal/Pest control ▸ Insecticidal activity

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC130H209N33O40S6

DescriptionStandard

        GVPCGESCVFIPCLTAVVGCSCSNKVCYLN
    

Molecular Weight3066.64 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0100

GRAVY Index0.98

Hydrophobic Moment 0.27

Boman Index0.33

Instability Index41.88

Aliphatic Index 90.67

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1140.29

LogP -13.33

H-bond Donors 44.0

H-bond Acceptors 46.0

Rotatable Bonds 93.0

Heavy Atoms 209.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0069859 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [Plant]

FamilyCyclotide

Tax ID60225

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Insecticidal

RECORD: Rec_0169874 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)