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MYP_108067
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Basic Information
Hc-15(Derived from Hc-CATH)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
15 amino acids
C88H154N28O17
Standard
Sequence
FKRLLKSVRRAVKKF
Physicochemical Analysis
1876.34 Da
12.00
6.76
6.55
0.4504
-0.43
0.99
-0.43
51.65
97.33
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.73
-4.61
30.0
24.0
68.0
133.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0230499 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hc-CATH
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli 1 (CIb)
18.8 μg/mL
MIC
Paper青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化; Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH. [J].生物工程学报,2021,37(07):2534-2542. DOI:10.13345/j.cjb.200583. PMID34327918 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34327918/
RECORD: Rec_0252283 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hc-CATH
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa (CI)
37.5 μg/mL
MIC
Paper青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化; Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH. [J].生物工程学报,2021,37(07):2534-2542. DOI:10.13345/j.cjb.200583. PMID34327918 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34327918/
RECORD: Rec_0360379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hc-CATH
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
37.5 μg/mL
MIC
Paper青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化; Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH. [J].生物工程学报,2021,37(07):2534-2542. DOI:10.13345/j.cjb.200583. PMID34327918 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34327918/
RECORD: Rec_0364136 VERIFIED: YES
Provenance & Taxonomy
Hydrophis cyanocinctus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. dysenteria
37.5 μg/mL
MIC
PMID28572668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28572668/
RECORD: Rec_0392266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hc-CATH
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans(CI)
150 μg/mL
MIC
Paper青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化; Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH. [J].生物工程学报,2021,37(07):2534-2542. DOI:10.13345/j.cjb.200583. PMID34327918 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34327918/
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