Peptide Database

Peptide NameBeta-defensin 127 (Beta-defensin 27) (DEFB-27) (Defensin; beta 127)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC507H827N135O140S9

DescriptionStandard

        MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALTLQDYVTIIENFPSLKTQST
    

Molecular Weight11342.40 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0558

GRAVY Index-0.14

Hydrophobic Moment 0.71

Boman Index0.01

Instability Index44.13

Aliphatic Index 94.55

Aromaticity 0.0707

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4441.24

LogP -36.64

H-bond Donors 156.0

H-bond Acceptors 156.0

Rotatable Bonds 378.0

Heavy Atoms 791.0

Ring Count 16.0

Amide Bonds 109.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0397489 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found