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MYP_108063
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Basic Information
RL-37
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
37 amino acids
C193H323N55O52
Standard
Sequence
RLGDILQKAREKIEGGLKKLVQKIKDFFGKFAPRTES
Physicochemical Analysis
4245.97 Da
10.12
4.76
4.54
0.1288
-0.68
0.77
-0.21
36.73
87.03
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1783.11
-14.23
62.0
57.0
154.0
300.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025844 VERIFIED: YES
Provenance & Taxonomy
Callithrix jacchus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0045625 VERIFIED: NO
Provenance & Taxonomy
Callithrix jacchus [Animal]
Cathelicidin
9483
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperAntibacterial protein LL-37 Evidence URLhttps://www.uniprot.org/uniprotkb/Q1KLY4/entry
RECORD: Rec_0070434 VERIFIED: YES
Provenance & Taxonomy
Platyrrhini [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
8-16 μM
MIC
PMID16720578 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16720578/
RECORD: Rec_0113496 VERIFIED: YES
Provenance & Taxonomy
Platyrrhini [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
In 20% SAB in SPB medium: Candida albicans
32 μM
MIC
PMID16720578 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16720578/
RECORD: Rec_0118816 VERIFIED: YES
Provenance & Taxonomy
Platyrrhini [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID16720578 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16720578/
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