Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC163H252N46O48S6

DescriptionStandard

        DHYICAKKGGTCNFSPCPLFNRIEGTCYSGKAKCC
    

Molecular Weight3816.41 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0796

GRAVY Index-0.31

Hydrophobic Moment 0.40

Boman Index-0.02

Instability Index40.25

Aliphatic Index 39.14

Aromaticity 0.1143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1511.96

LogP -17.86

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 122.0

Heavy Atoms 263.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105180 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)