Peptide Database

Peptide Nameα-helical CRF

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC166H273N45O54S2

DescriptionStandard

        DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA
    

Molecular Weight3827.34 Da

Isoelectric Point (pI)4.42

Net Charge (pH 7.0)-5.13

Net Charge (pH 7.4) -5.40

Charge Density (pH 7.0) -0.1555

GRAVY Index-0.23

Hydrophobic Moment 0.66

Boman Index-0.03

Instability Index50.40

Aliphatic Index 112.73

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1620.92

LogP -11.91

H-bond Donors 54.0

H-bond Acceptors 52.0

Rotatable Bonds 135.0

Heavy Atoms 267.0

Ring Count 2.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093566 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetCRF1 receptor (Human); CRF2 receptor (Rat); CRF2 receptor (Mouse)