Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC926H1406N210O284S9

DescriptionStandard

        IDDLAEIDYSLSSLPAVFQPFINLDLKGIVYPTGNYTAPPYMAAPFTIPDQRDSMLYLAFSEYFFQTSSFAYYTAGAFNVTIAEETCSYYNISTEIFGSIIPEVAKYSVTPNPVMLKIMATEIPNISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNITANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20312.89 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.51

Charge Density (pH 7.0) -0.0723

GRAVY Index0.22

Hydrophobic Moment 0.55

Boman Index0.23

Instability Index48.20

Aliphatic Index 90.66

Aromaticity 0.1311

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7833.50

LogP -84.97

H-bond Donors 265.0

H-bond Acceptors 280.0

Rotatable Bonds 644.0

Heavy Atoms 1429.0

Ring Count 36.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226919 VERIFIED: NO

Provenance & Taxonomy

OrganismOreotrochilus melanogaster [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria