Peptide Database

Peptide NameVigno 3

Function Ontology

Antimicrobial

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC117H187N35O40S6

DescriptionStandard

        GLPLCGETCVGGTCNTPGCSCSWPVCTRN
    

Molecular Weight2916.34 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0102

GRAVY Index0.13

Hydrophobic Moment 0.26

Boman Index0.14

Instability Index39.95

Aliphatic Index 46.90

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1174.30

LogP -18.26

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 85.0

Heavy Atoms 198.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0341191 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant],Viola ignobilis [Plant]

FamilyCyclotide

Tax ID214053

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Enzyme inhibitory Enzyme-inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme

RECORD: Rec_0420984 VERIFIED: NO