Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC349H566N84O92S3

DescriptionStandard

        MLEAMGFFGVGKPLATQIVNVVDAVGYAAIAVSTIMAILSAGGLAPTAAAIDFAIIYIKKKIANNLKAQAIVW
    

Molecular Weight7506.93 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0205

GRAVY Index1.04

Hydrophobic Moment 0.49

Boman Index0.44

Instability Index6.14

Aliphatic Index 129.86

Aromaticity 0.0822

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2755.79

LogP -17.94

H-bond Donors 93.0

H-bond Acceptors 97.0

Rotatable Bonds 245.0

Heavy Atoms 528.0

Ring Count 9.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012337 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus sp. DNRA2 [Bacterium]

FamilyBacteriocin

Tax ID2723053

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal