Peptide Database

Peptide NameMBD-4 (11-40) (P9 [H21R,K23R,K28R], P9R)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC144H232N52O35S5

DescriptionStandard

        NGAICWGPCPTAFRQIGNCGRFRVRCCRIR
    

Molecular Weight3412.03 Da

Isoelectric Point (pI)10.46

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.1903

GRAVY Index-0.15

Hydrophobic Moment 0.74

Boman Index-0.15

Instability Index12.80

Aliphatic Index 55.33

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1426.33

LogP -16.34

H-bond Donors 57.0

H-bond Acceptors 46.0

Rotatable Bonds 107.0

Heavy Atoms 236.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400656 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anti-SARS-CoV-2 Cytotoxic

TargetVero-E6 cells

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