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MYP_107889
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Basic Information
Tyr-Melanocyte-stimulating hormone (MSH) release-inhibiting factor
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Standard
4 amino acids
C22H32N4O6
Standard
Sequence
YPLG
Physicochemical Analysis
448.51 Da
5.52
-0.24
-0.45
-0.0602
0.12
0.21
0.48
38.35
97.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
162.06
-0.02
5.0
6.0
10.0
32.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020407 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0089195 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0215467 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
N-Tyr-MIF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for N-Tyr-MIF-1 (Homo sapiens): PMID 8105102 PMID8105102 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8105102/
RECORD: Rec_0268345 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
RECORD: Rec_0311226 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
Gliadin-derived
4565;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperMycroft F. J., Bhargava H. N., Wei E. T.. Pharmacological activities of the MIF-1 analogues Pro-Leu-Gly, Tyr-Pro-Leu-Gly and pareptide. Peptides. 8, 1051-1055, 1987.
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