Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC450H724N134O134S8

DescriptionStandard

        MRTLAVLAAILLFTLQAQAESLQERADEVATQEQPGSGSAYPFPHLPPCAGPSLLSTGSQARRTCYCRNKRCFTPEFDAGKCKVERRTYKLCCR
    

Molecular Weight10411.90 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0482

GRAVY Index-0.35

Hydrophobic Moment 0.63

Boman Index-0.10

Instability Index58.46

Aliphatic Index 66.60

Aromaticity 0.0745

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4321.66

LogP -48.97

H-bond Donors 158.0

H-bond Acceptors 148.0

Rotatable Bonds 338.0

Heavy Atoms 726.0

Ring Count 15.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395987 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence