Peptide Database

Peptide NameBeta-defensin 124 (Defensin, beta 124; Defensin, beta 126; primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC252H383N69O71S7

DescriptionStandard

        EFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
    

Molecular Weight5739.61 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.96

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0400

GRAVY Index-0.70

Hydrophobic Moment 0.40

Boman Index-0.13

Instability Index80.96

Aliphatic Index 43.88

Aromaticity 0.1224

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2233.85

LogP -19.72

H-bond Donors 83.0

H-bond Acceptors 82.0

Rotatable Bonds 179.0

Heavy Atoms 399.0

Ring Count 14.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223716 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0391628 VERIFIED: NO