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MYP_107884
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C139H221N35O42S6
Standard
Sequence
GTFPCGESCVFIPCLTSAIGCSCKSKVCYKN
Physicochemical Analysis
3246.84 Da
8.33
1.70
1.40
0.0548
0.47
0.33
0.19
37.19
59.68
0.0968
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1218.80
-14.81
48.0
50.0
102.0
222.0
5.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0159596 VERIFIED: NO
Provenance & Taxonomy
Viola biflora [Plant]; Viola tricolor [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-21; 9-23; 14-28
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0171859 VERIFIED: NO
Provenance & Taxonomy
Viola biflora [Plant]
Cyclotide
214529
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
disulfide-stabilized; exact pairings not extracted
cystine-knot scaffold
Bio-Activity Profile
Anticancer Antimicrobial
PaperPlant Antimicrobial Oligopeptides with Anticancer Properties as a Source of Biologically Active Peptides—An In Silico Study PMID41009751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/41009751/
RECORD: Rec_0195735 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Defensin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21; 9-23; 14-28
Bio-Activity Profile
Cytotoxic Anticancer
Human lymphoma cell line U-937 GTB
0.96 μM
IC50
PaperPubMed PMID: 18191970 PMID18191970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18191970/
RECORD: Rec_0196245 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 22.6%, E 22.6%, T 29.0%, C 25.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0244588 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]; Viola biflora [Plant]; Psychotria leptothyrsa [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Anticancer Cytotoxic Antimicrobial
Human histiocytic lymphoma U-937/GTB
0.96±0.1 μM
IC50
PaperPubMed PMID 18191970 PMID18191970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18191970/
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