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MYP_107834
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Basic Information
Kinin 3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Renin inhibition ▸ Renin inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C13H15N3O3
Standard
Sequence
WG
Physicochemical Analysis
261.28 Da
5.53
-0.24
-0.44
-0.1200
-0.65
0.43
0.65
-46.85
0.00
0.5000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
108.21
0.24
4.0
3.0
5.0
19.0
2.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030774 VERIFIED: NO
Provenance & Taxonomy
Nephrops norvegicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0109852 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
ACE-inhibitory peptide
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperPeptides with angiotensin I converting enzyme (ACE) inhibitory activity generated from porcine skeletal muscle proteins by the action of meat-borne Lactobacillus. PMID23806758 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23806758/
RECORD: Rec_0122331 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperTorkova A., Kononikhin A., Bugrova A., Khotchenkov V., Tsentalovich M., Medvedeva U.. Effect of in vitro gastrointestinal digestion on bioactivity of poultry protein hydrolysate. Curr. Res. Nutr. Food Sci., 4 (SI 2), 77-86, 2016.
RECORD: Rec_0129567 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
5900.0
IC50
PaperCheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.. Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407, 1980.
RECORD: Rec_0153457 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID32806659 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32806659/
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